The Growth Characteristics of Patients with Noonan Syndrome: Results of Three Years of Growth Hormone Treatment: A Nationwide Multicenter Study
Author(s) -
Zeynep Şıklar,
Mikayir Genenş,
Şükran Poyrazoğlu,
Firdevs Baş,
Feyza Darendelıler,
Rüveyde Bundak,
Zehra Aycan,
Şenay Savaş Erdeve,
Semra Çeti̇nkaya,
Ayla Güven,
Saygın Abalı,
Zeynep Atay,
Serap Turan,
Cengiz Kara,
Gülay Can Yılmaz,
Nesibe Akyürek,
Ayhan Abacı,
Gamze Çelmeli,
Erkan Sarı,
Semih Bolu,
Hüseyin Anıl Korkmaz,
Enver Şimşek,
Gönül Çatlı,
Muammer Büyükinan,
Atilla Çayır,
Olcay Evliyaoğlu,
Pınar İşgüven,
İlker Tolga Özgen,
Nihal Hatipoğlu,
Atilla Halil Elhan,
Merih Berberoğlu
Publication year - 2016
Publication title -
journal of clinical research in pediatric endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.566
H-Index - 35
eISSN - 1308-5735
pISSN - 1308-5727
DOI - 10.4274/jcrpe.3013
Subject(s) - medicine , short stature , ptpn11 , noonan syndrome , pediatrics , growth hormone deficiency , growth hormone , bone age , hormone , cancer , colorectal cancer , kras
Noonan syndrome (NS) is a multisystem disorder, and short stature is its most striking manifestation. Optimal growth hormone (GH) treatment for NS is still controversial. In this study, using a nationwide registration system, we aimed to evaluate the growth characteristics and the clinical features of NS patients in Turkey and their growth response to GH treatment.
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