Adding Multiple Adipokines into the Model do not Improve Weight Gain Prediction by Leptin Levels in Newborns | Zendy

Consuelo TreviñoGarza | Zendy; Cynthia M. EstradaZúñiga | Zendy; Leonardo MancillasAdame | Zendy; Laura VillarrealMartínez | Zendy; Jesús Zacarías VillarrealPérez | Zendy; Isaías RodríguezBalderrama | Zendy; Fernando MontesTapia | Zendy; Manuel Enrique de la O-Cavazos | Zendy

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Adding Multiple Adipokines into the Model do not Improve Weight Gain Prediction by Leptin Levels in Newborns

Author(s) -

Consuelo TreviñoGarza,

Cynthia M. EstradaZúñiga,

Leonardo MancillasAdame,

Laura VillarrealMartínez,

Jesús Zacarías VillarrealPérez,

Isaías RodríguezBalderrama,

Fernando MontesTapia,

Manuel Enrique de la O-Cavazos

Publication year - 2016

Publication title -

journal of clinical research in pediatric endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.566

H-Index - 35

eISSN - 1308-5735

pISSN - 1308-5727

DOI - 10.4274/jcrpe.2693

Subject(s) - adipokine , medicine , resistin , leptin , weight gain , adiponectin , adipose tissue , endocrinology , obesity , body weight , insulin resistance

Most adipose tissue programming is realized in early life. Also, the postnatal three months, rather than the later phases of infancy, may be more relevant in the development of an adverse cardiometabolic risk profile. The adipokines phenotype, as a predictor of early-life weight gain, has been recently explored in cord blood. To determine whether in addition to leptin levels in cord samples, adiponectin, interleukin-6 (IL-6), monocyte chemoattractant protein-1 (MCP-1), resistin, plasminogen activator inhibitor-1 (PAI-1), and tumor necrosis factor alpha (TNF-α) levels improve weight gain prediction during the first three months of life.

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