Distribution of RET Mutations and Evaluation of Treatment Approaches in Hereditary Medullary Thyroid Carcinoma in Turkey | Zendy

Berna İmge Aydoğan | Zendy; Bağdagül Yüksel | Zendy; Mazhar Müslüm Tuna | Zendy; Mehtap Navdar Başaran | Zendy; Ayşen Akkurt | Zendy; Melek Eda Ertörer | Zendy; Kadriye Aydın | Zendy; Sibel Güldiken | Zendy; Yasin Şimşek | Zendy; Züleyha Karaca | Zendy; Merve Yılmaz | Zendy; Müjde Aktürk | Zendy; İnan Anaforoğlu | Zendy; Nur Kebapçı | Zendy; Cevdet Duran | Zendy; Abdullah Taşlıpınar | Zendy; Mustafa Kulaksızoğlu | Zendy; Alptekin Gürsoy | Zendy; Selçuk Dağdelen | Zendy; Murat Faik Erdoğan | Zendy

Open Access

Distribution of RET Mutations and Evaluation of Treatment Approaches in Hereditary Medullary Thyroid Carcinoma in Turkey

Author(s) -

Berna İmge Aydoğan,

Bağdagül Yüksel,

Mazhar Müslüm Tuna,

Mehtap Navdar Başaran,

Ayşen Akkurt,

Melek Eda Ertörer,

Kadriye Aydın,

Sibel Güldiken,

Yasin Şimşek,

Züleyha Karaca,

Merve Yılmaz,

Müjde Aktürk,

İnan Anaforoğlu,

Nur Kebapçı,

Cevdet Duran,

Abdullah Taşlıpınar,

Mustafa Kulaksızoğlu,

Alptekin Gürsoy,

Selçuk Dağdelen,

Murat Faik Erdoğan

Publication year - 2016

Publication title -

journal of clinical research in pediatric endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.566

H-Index - 35

eISSN - 1308-5735

pISSN - 1308-5727

DOI - 10.4274/jcrpe.2219

Subject(s) - medicine , thyroidectomy , medullary cavity , thyroid carcinoma , multiple endocrine neoplasia type 2 , mutation , genetic testing , multiple endocrine neoplasia , calcitonin , retrospective cohort study , gastroenterology , pheochromocytoma , medullary thyroid cancer , oncology , thyroid , pediatrics , germline mutation , genetics , biology , gene

This retrospective multicenter study, centrally conducted and supported by the Society of Endocrinology and Metabolism of Turkey, aimed to evaluate the impact of free RET proto-oncogene testing in medullary thyroid carcinoma (MTC) patients. Surgical timing, adequacy of the treatment, and frequency of prophylactic thyroidectomy (PTx) in mutation carriers were also assessed.

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