Mitochondrial ATPase Subunit 6 and Cytochrome B Gene Variations in Obese Turkish Children
Author(s) -
Durkadın Demir,
Doğa Türkkahraman,
Anıl Aktaş Samur,
Güven Lüleci,
Sema Akçurin,
Özgül M. Alper
Publication year - 2014
Publication title -
journal of clinical research in pediatric endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.566
H-Index - 35
eISSN - 1308-5735
pISSN - 1308-5727
DOI - 10.4274/jcrpe.1601
Subject(s) - nonsynonymous substitution , genetics , synonymous substitution , gene , mitochondrial dna , biology , medicine , genome , codon usage bias
Due to the importance of energy metabolism in mitochondria, mitochondrial genome variations are evaluated in energy-related diseases such as obesity. To date, several nuclear genes were found to be related to obesity. Our aim in this study was to investigate the presence of polymorphisms in mitochondrial ATPase subunit 6 (mt-ATP6) and cytochrome b (mt-CytB) genes that may be associated with childhood obesity.
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