Lack of Association Between Peripheral Activity of Thyroid Hormones and Elevated TSH Levels in Childhood Obesity | Zendy

Denisa Lobotková | Zendy; Daniela Staníková | Zendy; Juraj Staník | Zendy; O Cervenová | Zendy; Vladimı́r Bzdúch | Zendy; Ľubica Tichá | Zendy

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Lack of Association Between Peripheral Activity of Thyroid Hormones and Elevated TSH Levels in Childhood Obesity

Author(s) -

Denisa Lobotková,

Daniela Staníková,

Juraj Staník,

O Cervenová,

Vladimı́r Bzdúch,

Ľubica Tichá

Publication year - 2014

Publication title -

journal of clinical research in pediatric endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.566

H-Index - 35

eISSN - 1308-5735

pISSN - 1308-5727

DOI - 10.4274/jcrpe.1251

Subject(s) - medicine , endocrinology , hormone , thyroid , reverse triiodothyronine , triiodothyronine , hypothalamic–pituitary–thyroid axis , obesity , thyroid stimulating hormone , peripheral , thyroid hormones

An elevated thyroid stimulating hormone (TSH) level is a frequent finding in obese children, but its association with peripheral hormone metabolism is not fully understood. We hypothesized that in obesity, the changes in thyroid hormone metabolism in peripheral tissues might lead to dysregulation in the thyroid axis. The purpose of this study was to investigate the association of TSH with thyroid hormones in a group of obese children as compared to normal-weight controls.

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