Evaluation of Risk Factors for Hepatosteatosis in Gall Stone Disease

Aim: It has been reported that non-alcoholic fatty liver disease\ud(NAFLD) was associated with cholecystectomy and cholecystectomy\udthat may be a risk factor for the development of non-alcoholic fatty\udliver disease. In this sense, we studied the other risk factors for nonalcoholic\udfatty liver disease in patients with cholelythiasis.\udMethods: In this study, we included 204 consecutive patients\udwho underwent elective cholecystectomy between June 2011 and\udJanuary 2014 due to cholelythiasis. We retrospectively evaluated\udthe files of the patients, including operative findings, history,\udlaboratory and radiological imaging findings obtained from the\udhospital information system and the archived contents of the files.\udResults: There was no significant relationship between the\udnumber and size of the stones and hepatic steatosis (p=0.83 and\udp=0.96, respectively). Besides, there was no statistically significant\udrelationship between gender and hepatosteatosis. In multivariate\udregression, obesity, type 2 diabetes mellitus (DM) and cholelithiasis\udwere identified as an independent risk factor for NAFLD.\udConclusion: NAFLD and cholelithiasis are common in the general\udpopulation and have common risk factors. Obesity, female gender,\udage, type 2 DM, hypertriglyceridemia, insulin resistance, metobolic\udsyndrome, fast weight loss, and bile stasis are risk factors for\udcholelithiasis. (The Medical Bulletin of Haseki 2015; 53: 237-40