Association of complete blood count parameters with IgE levels and disease severity, atopy type in allergic rhinitis patients

Other than rhinitis, adult AR patients may have concurrent conjunctivitis, sinusitis and asthma. Bilateral eye itching, redness, burning, photophobia, watering and conjunctival edema may occur in allergic conjunctivitis patients (3). In addition to the history and physical examination findings of the patients, skin prick and allergen specific immunoglobulin E (IgE) tests including aeroallergens are used in AR diagnosis. AR is classified as intermittent or persistent based on the duration of the symptoms and as mild or moderate/severe based on the severity of the disease (4). AR occurs as the result of IgE mediated type 1 hypersensitivity reaction against inhaled allergen (mostly pollen and mite). Typical symptoms and findings occur with the effect of mediators (such as histamine, leukotrienes) released from IgE-related mast cells in this inflammation accompanied by eosinophils (2,5,6). The objective of this study was to investigate whether there was a relation between allergen sensitivity, disease severity DOI: 10.4274/gulhane.galenos.2020.900 ORIGINAL ARTICLE