Open AccessVariation in vector competence for dengue 2 virus among 24 collections of Aedes aegypti from Mexico and the United States.
Author(s) -
Kristine E. Bennett,
Ken E. Olson,
Marı́a de Lourdes Muñoz,
Ildefonso Fernández-Salas,
José A. Farfán-Ale,
S. Higgs,
William C. Black,
Barry J. Beaty
Publication year - 2002
Publication title -
american journal of tropical medicine and hygiene
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.015
H-Index - 151
eISSN - 1476-1645
pISSN - 0002-9637
DOI - 10.4269/ajtmh.2002.67.85
Subject(s) - aedes aegypti , dengue fever , midgut , biology , vector (molecular biology) , virology , dengue virus , yellow fever , population , veterinary medicine , virus , ecology , larva , medicine , environmental health , genetics , gene , recombinant dna
Aedes aegypti from 24 collections in Mexico and the United States were challenged orally with dengue 2 virus JAM1409 (DEN-2 JAM1409). The vector competence (VC) of the populations ranged from 24% to 83%. Mosquito populations from the Yucatan exhibited greater VC than those from other areas of Mexico. The presence or absence of a midgut infection barrier (MIB) and a midgut escape barrier (MEB) was determined for mosquitoes in each population. The percentage of mosquitoes exhibiting an MIB ranged from 14% to 59%, and those exhibiting an MEB ranged from 4% to 43% in the collections. The MIB and MEB were not completely independent as determined by regression analysis. Midgut infection rates were dose dependent.
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