Open AccessDiagnosis of Schistosoma haematobium Infection with a Mobile Phone-Mounted Foldscope and a Reversed-Lens CellScope in Ghana
Author(s) -
Richard K. D. Ephraim,
Evans Duah,
James S. Cybulski,
Manu Prakash,
Michael V. D’Ambrosio,
Daniel A. Fletcher,
Jennifer Keiser,
Jason R. Andrews,
Isaac I. Bogoch
Publication year - 2015
Publication title -
american journal of tropical medicine and hygiene
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.015
H-Index - 151
eISSN - 1476-1645
pISSN - 0002-9637
DOI - 10.4269/ajtmh.14-0741
Subject(s) - schistosoma haematobium , mobile phone , filter (signal processing) , lens (geology) , microscope , filter paper , microscopy , biology , medicine , computer science , pathology , immunology , schistosomiasis , computer vision , chromatography , helminths , chemistry , telecommunications , paleontology
We evaluated two novel, portable microscopes and locally acquired, single-ply, paper towels as filter paper for the diagnosis of Schistosoma haematobium infection. The mobile phone-mounted Foldscope and reversed-lens CellScope had sensitivities of 55.9% and 67.6%, and specificities of 93.3% and 100.0%, respectively, compared with conventional light microscopy for diagnosing S. haematobium infection. With conventional light microscopy, urine filtration using single-ply paper towels as filter paper showed a sensitivity of 67.6% and specificity of 80.0% compared with centrifugation for the diagnosis of S. haematobium infection. With future improvements to diagnostic sensitivity, newer generation handheld and mobile phone microscopes may be valuable tools for global health applications.
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