EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1)
Author(s) -
Luigi Cristiano
Publication year - 2020
Publication title -
atlas of genetics and cytogenetics in oncology and haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.121
H-Index - 2
ISSN - 1768-3262
DOI - 10.4267/2042/70858
Subject(s) - translation (biology) , genetics , elongation , elongation factor , eukaryotic translation , biology , gene , factor (programming language) , dna , microbiology and biotechnology , computer science , rna , messenger rna , materials science , ribosome , metallurgy , ultimate tensile strength , programming language
Eukaryotic translation elongation factor 1 epsilon 1, alias EEF1E1, is a protein-coding gene that plays a role in the elongation step of translation. In particular, it is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex (MARS). Its expression is found frequently altered in human cancer cells and it is considered a putative tumor suppressor gene. This review collects the data on DNA/RNA, the protein encoded and the diseases where EEF1E1 is involved.
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