Follicular dendritic cell in lymphomas of follicular origin | Zendy

Antonino Carbone | Zendy; Annunziata Gloghini | Zendy

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Follicular dendritic cell in lymphomas of follicular origin

Author(s) -

Antonino Carbone,

Annunziata Gloghini

Publication year - 2019

Publication title -

atlas of genetics and cytogenetics in oncology and haematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.121

H-Index - 2

ISSN - 1768-3262

DOI - 10.4267/2042/70183

Subject(s) - follicular phase , follicular lymphoma , biology , follicular dendritic cells , follicular cell , b cell , cancer research , lymphoma , pathology , genetics , immunology , medicine , t cell , immune system , antibody , antigen presenting cell

B-cell lymphomas of presumed follicular origin include follicular lymphoma (FL), mantle cell lymphoma (MCL) and marginal zone lymphoma (MZL). Within the microenvironment of all these follicle-derived lymphomas tumor cells show a strict topographical and functional relationship with FDCs, together with reactive lymphoid and stromal cells. The FDC patterns, as described for FL and MCL, are reminiscent of the distribution pattern of FDC meshwork seen in the GC or the mantle zone of the secondary lymphoid follicle, respectively.

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