Open Accesst(1;5)(p32;q31) without TAL1 rearrangement
Author(s) -
Adriana Zámečnı́kova
Publication year - 2018
Publication title -
atlas of genetics and cytogenetics in oncology and haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.121
H-Index - 2
ISSN - 1768-3262
DOI - 10.4267/2042/68911
Subject(s) - genetics , biology
1p32 translocations and submicroscopic interstitial deletions resulting in TAL1 deregulation are known aberrations in T lymphoblastic leukemia/lymphoma. The t(1;5)(p32;q31) is a rare translocation of 1p32 described only in 1 patient with aberrantly expressed TAL1 mRNA and protein (François et al., 1998) and in 2 other patients without involvement of the TAL1 gene.
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