Open AccessARHGAP21 (Rho GTPase activating protein 21)
Author(s) -
Mariana Ferreira Pissarra,
Sara Teresinha Olalla Saad,
Mariana Lazarini
Publication year - 2018
Publication title -
atlas of genetics and cytogenetics in oncology and haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.121
H-Index - 2
ISSN - 1768-3262
DOI - 10.4267/2042/68537
Subject(s) - genetics , gene , biology , microbiology and biotechnology , gtpase , computational biology
ARHGAP21 is a Rho GTPase-activating protein (RhoGAP). Like other members of the RhoGAP family, ARHGAP21 enhances the intrinsic GTPase activity of small Rho GTPases, leading to their inactivation. ARHGAP21 participates in cellular proliferation, adhesion, migration and vesicle traffic. This review comprises information on DNA/RNA, the encoded protein and protein functions.
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