Open AccessLymphocyte depletion classical Hodgkin lymphoma
Author(s) -
Antonino Carbone,
Annunziata Gloghini
Publication year - 2018
Publication title -
atlas of genetics and cytogenetics in oncology and haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.121
H-Index - 2
ISSN - 1768-3262
DOI - 10.4267/2042/68129
Subject(s) - lymphoma , cancer research , classical hodgkin lymphoma , hodgkin lymphoma , biology , lymphocyte , gene , immunology , genetics , medicine
The lymphocyte depletion classical Hodgkin lymphoma (LDCHL) is the less common subtype of cHL. In LDCHL, Hodgkin and Reed-Sternberg (HRS) cells grow within a background depleted in reactive lymphocytes. LDCHL subtype accounts for only a small fraction of all HL cases in Western countries. It also occurs in people with HIV/AIDS. The HRS cells show the same immunophenotype as in the other subtypes of cHL.
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