TNFRSF17 (tumor necrosis factor receptor superfamily, member 17) | Zendy

Abigail Gillespie | Zendy; Eric Sanchez | Zendy; George Tang | Zendy; Haiming Chen | Zendy; James Berenson | Zendy

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TNFRSF17 (tumor necrosis factor receptor superfamily, member 17)

Author(s) -

Abigail Gillespie,

Eric Sanchez,

George Tang,

Haiming Chen,

James Berenson

Publication year - 2017

Publication title -

atlas of genetics and cytogenetics in oncology and haematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.121

H-Index - 2

ISSN - 1768-3262

DOI - 10.4267/2042/62477

Subject(s) - superfamily , tumor necrosis factor receptor , cancer research , biology , tumor necrosis factor alpha , vascular endothelial growth inhibitor , gene , genetics , receptor , immunology , vascular endothelial growth factor a , vascular endothelial growth factor , vegf receptors

B Cell Maturation Antigen (BCMA) is a transmembrane signaling protein preferentially expressed on plasma cells. Its ligands include BCell Activating Factor (BAFF) and A Proliferation Inducing Ligand (APRIL). BCMA is involved in JNK and NF-kB activation pathways that induce Bcell development and autoimmune responses. BCMA has been implicated in autoimmune disorders as well as B-lymphocyte malignancies.

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