MAFB (v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B) | Zendy

Carolina VicenteDueñas | Zendy; Inés GonzálezHerrero | Zendy; Idoia GarcíaRamírez | Zendy; Isidro Sánchez-Garcı́a | Zendy

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MAFB (v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B)

Author(s) -

Carolina VicenteDueñas,

Inés GonzálezHerrero,

Idoia GarcíaRamírez,

Isidro Sánchez-Garcı́a

Publication year - 2017

Publication title -

atlas of genetics and cytogenetics in oncology and haematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.121

H-Index - 2

ISSN - 1768-3262

DOI - 10.4267/2042/62188

Subject(s) - ht1080 , biology , fibrosarcoma , oncogene , genetics , gene , cancer research , dna , microbiology and biotechnology , cell cycle

The MAFB protein is a basic leucine zipper (bZIP) transcription factor that plays important roles both in development and in the regulation of lineagespecific hematopoiesis. This gene contains no introns. The abnormal function of MAFB has been implicated in multiple myeloma, myeloid leukemias, multicentric carpotarsal osteolysis, Dupuytren's disease and nonsyndromic cleft lip.

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