FABP5 (fatty acid binding protein 5 (psoriasis-associated)) | Zendy

Erin F. Balcom | Zendy; RongZong Liu | Zendy; Stanley Poon | Zendy; Roseline Godbout | Zendy

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FABP5 (fatty acid binding protein 5 (psoriasis-associated))

Author(s) -

Erin F. Balcom,

RongZong Liu,

Stanley Poon,

Roseline Godbout

Publication year - 2017

Publication title -

atlas of genetics and cytogenetics in oncology and haematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.121

H-Index - 2

ISSN - 1768-3262

DOI - 10.4267/2042/62185

Subject(s) - fatty acid binding protein , psoriasis , gene , chemistry , genetics , biochemistry , biology , medicine , dermatology

The FABP5 gene encodes a member of the fatty acid binding protein family which is also known as epidermal or cutaneous FABP. Overexpression of FABP5 is associated with a number of cancers including breast and prostate cancers, as well as psychiatric disorders and diabetes. FABP5 can bind retinoic acid as well as polyunsaturated and saturated fatty acids. Transport of FABP5 ligands such as arachidonic acid and retinoic acid to the nucleus is believed to activate the nuclear receptor peroxisome proliferator-activated receptor beta/delta (PPARβ/δ).

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