Open AccessThyroid: Medullary carcinoma
Author(s) -
Yash R. Somnay,
David Schneider,
Haggi Mazeh
Publication year - 2013
Publication title -
atlas of genetics and cytogenetics in oncology and haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.121
H-Index - 2
ISSN - 1768-3262
DOI - 10.4267/2042/48876
Subject(s) - thyroid , medullary cavity , pathology , context (archaeology) , thyroid carcinoma , medicine , medullary carcinoma , neuroendocrine tumors , medullary thyroid cancer , biology , paleontology
Medullary thyroid cancers (MTC) are rare neuroendocrine tumors arising from the parafollicular C-cells of the thyroid. In this review, we provide a general overview of the classification, pathology, and clinical management of MTC. In the latter half, we survey the underlying genetic framework of MTC and its potential implications within a diagnostic and therapeutic context.