Freeman K-set

Figure 1: A. Topological hierarchy of K-sets, in which (+) means excitation and () means inhibition. B. Simulated impulse responses for open loop (interactions are suppressed by anesthesia), mutual excitation (KIe), and negative feedback (KII). C. Experimental open loop impulse response fitted with solution to an ODE representing the dynamics of an ensemble of neurons made non-interactive by anesthesia and modeled with a KOe set. The same forms hold for the KOi set. The rate constants have been shown to hold in closed-loop interactive states. From (Freeman, 1975, Fig. 1.6, p. 40). Dr. Walter J. Freeman, University of California, Berkeley, California