Genome-wide association study of meat quality traits in chicken | Zendy

Tao Zhang | Zendy; Q.C. Fan | Zendy; J.Y. Wang | Zendy; G.X. Zhang | Zendy; Yangshun Gu | Zendy; You Tang | Zendy

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Genome-wide association study of meat quality traits in chicken

Author(s) -

Tao Zhang,

Q.C. Fan,

J.Y. Wang,

G.X. Zhang,

Yangshun Gu,

You Tang

Publication year - 2015

Publication title -

genetics and molecular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.356

H-Index - 48

ISSN - 1676-5680

DOI - 10.4238/2015.september.8.6

Subject(s) - single nucleotide polymorphism , candidate gene , biology , genetics , genome wide association study , snp , gene , genetic association , quantitative trait locus , genome , bonferroni correction , genotype , statistics , mathematics

Meat quality traits are very important in the poultry industry. To identify single nucleotide polymorphisms (SNPs) and candidate genes affecting meat quality traits, a genome-wide association study was performed using the Illumina chicken 60K SNP beadchip in Jinghai yellow chicken. Four meat quality traits were measured. Two SNPs reached 5% Bonferroni genome-wide significance (P < 1.8E-6) and 7 SNPs reached "suggestive" genome-wide significance (P < 3.59E-6) with meat quality. These SNPs were located nearby or in 7 candidate genes, including CBLN2, HPGDS, SETD2, and ANKRD46, among others. A total of 5650 haplotpyes were established and only 1 was found to be associated with fat content in leg muscle. These results indicate that the 9 SNPs and 7 genes are important candidate markers and may influence meat quality traits in chicken.

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