English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The  frequency of micronuclei in both buccal cells and peripheral blood lymphocytes  is extensively used as a biomarker of chromosomal damage and genome stability  in human populations. We examined whether prolonged exposure to complex  mixtures of pesticides leads to an increase in cytogenetic damage. The exposed  group comprised 50 agricultural aviators, mainly from Central and Southeast  regions of Brazil, who had inhaled agrochemicals for more than 10 years without  personal protection equipment; the control group consisted of 17 men from the  same regions, without indication of exposure to pesticides, There were three  times higher frequencies of micronuclei (P &lt; 0.05) and 2.5 times higher  frequencies of binucleated cells in the aviators when compared to controls.  However, cytotoxic alterations such as broken eggs and karyorrhexis did not  present statistically significant differences between the exposed and control  groups. Therefore, diverse agrochemicals used to combat pests in agriculture  possess genotoxic effects in the oral mucosa of the agricultural pilots, as  showed in this study.

Short Communication Cytogenetic damage in the buccal epithelium of Brazilian aviators occupationally exposed to agrochemicals