Feasibility of Performing Sentinel Lymph Node Biopsy (SLNB) after Mastectomy: A Case Report
Author(s) -
Hanadi Bu-Ali,
Eleftherios P. Mamouna
Publication year - 2010
Publication title -
journal of cancer therapy
Language(s) - English
Resource type - Journals
eISSN - 2151-1942
pISSN - 2151-1934
DOI - 10.4236/jct.2010.12015
Subject(s) - medicine , sentinel lymph node , ductal carcinoma , mastectomy , axilla , biopsy , contraindication , surgery , axillary dissection , total mastectomy , sentinel node , dissection (medical) , breast cancer , radiology , cancer , pathology , alternative medicine
Previous mastectomy remains a contraindication to SLNB as normal drainage patterns of the breast can be disturbed. Patients diagnosed with DCIS on core biopsy and later found to have microinvasive or invasive carci-noma at the time of mastectomy are deprived of the opportunity for SLNB and need to undergo axillary dissection. We explored the option and feasibility of performing SLNB in a 39-year-old female who underwent a simple mastectomy without axillary sampling for extensive DCIS and later found to have microinvasive ductal carcinoma on permanent pathology. Results: Lymphatic mapping using subdermal injection of 99mTc-labeled sulfur colloid and blue dye led to the identification of five SLNs. Histopathologic examination showed no metastasis. Conclusion: SNLB is feasible in this setting. However, before its use is routinely adopted, its feasibility and accuracy has to be demonstrated in larger num-bers of patients in whom a negative SLNB is followed by a completion axillary dissection
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