Head and Neck Cancer a Single Institution Experience: King Abdulaziz University
Author(s) -
Rolina K. Al-Wassia,
Nisreen A. Awad,
Shadi Alkhayyat,
Atlal Abusanad,
Hani AlMarzouki,
Mohammed Attar,
Talal Al Khatib,
C. Constantinescu
Publication year - 2015
Publication title -
journal of king abdulaziz university-medical sciences
Language(s) - English
Resource type - Journals
ISSN - 1319-1004
DOI - 10.4197/med.22-3.2
Subject(s) - medicine , radiation therapy , head and neck cancer , logistic regression , overall survival , surgery
The purpose of this study is to assess the loco-regional control and overall survival in head and neck cancer patients, as well as evaluate the clinical benefit of intensity-modulated radiotherapy implemented in 2011 at our Hospital. Data of 117 patients between 2007 and 2014 was reviewed retrospectively. Cumulative survival and disease control rates were calculated by Kaplan-Meier product-limit actuarial method. Loco-regional control and survival rates for intensity modulated and three-dimensional conformal radiotherapy were compared by a logistic regression test. After a median follow-up of 12 months, 53 (51%) patients who underwent radical radiotherapy were free of disease, 43 (42%) with disease, and seven (7%) unknown. During this time, 31 (26%) patients died from the disease. Using actuarial estimates for the two-year follow-up, this study found that significant gains in survival were obtained by switching treatment modalities. The benchmarking gives reassurance that our results are comparable to the best clinical practices internationally.
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