Open AccessEffects Of A Novel Dental Gel On Plaque And Gingivitis: A Comparative Study
Author(s) -
Mohammad Dadkhah,
Chung Ne,
Janet Ajdaharian,
Cherie Wink,
Perry R. Klokkevold,
Petra WilderSmith
Publication year - 2014
Publication title -
dentistry
Language(s) - English
Resource type - Journals
ISSN - 2161-1122
DOI - 10.4172/2161-1122.1000239
Subject(s) - gingival inflammation , gingivitis , medicine , dentistry , dental plaque , gingival sulcus , dentifrice , bleeding on probing , gingival and periodontal pocket , periodontitis , chemistry , inorganic chemistry , fluoride
Objectives The goal of this prospective, randomized, controlled, double-blinded study was to evaluate the effects of a novel dental gel on plaque and gingival health. The dental gel was designed to (1) break up and prevent re-accumulation of microbial biofilm, and (2) inhibit metal mediated inflammation. Materials and Methods Twenty-five subjects with moderate gingival inflammation (Löe and Silness Gingival Index ≥2) and pocket depths <4 were randomly assigned to brush twice daily for 21 days with the test or the control dental gel. On Days 0, 7, 14 and 21, plaque levels (Quigley-Hein, Turesky Modification Plaque Index), gingival inflammation (Löe and Silness Gingival Index) and gingival bleeding (modified Sulcus Bleeding Index) were determined by one blinded, investigator using a pressure sensitive probe. Results After 3 weeks, all 3 clinical indices were significantly improved in both groups (P<0.05) and significantly lower in the test group (P<0.05). Conclusion The novel dental gel formulation was provided effective plaque control and reduced gingival inflammation. Clinical Relevance A novel dentifrice formulation may be an effective tool for plaque removal and maintaining gingival health.