Open AccessBlood Derived Induced Pluripotent Stem Cells (iPSCs): Benefits, Challenges and the Road Ahead
Author(s) -
Jimmy El Hokayem,
Holly N. Cukier,
Derek M. Dykxhoorn
Publication year - 2016
Publication title -
journal of alzheimer's disease and parkinsonism
Language(s) - English
Resource type - Journals
ISSN - 2161-0460
DOI - 10.4172/2161-0460.1000275
Subject(s) - induced pluripotent stem cell , context (archaeology) , neuroscience , human induced pluripotent stem cells , medicine , biology , embryonic stem cell , genetics , paleontology , gene
Since the creation of induced Pluripotent Stem Cells (iPSCs) ten years ago, hundreds of publications have demonstrated their considerable impact on disease modeling and therapy. In this commentary, we will summarize key milestones, benefits and challenges in the iPSC field. Furthermore, we will highlight blood as an effective and easily accessible source for patient-specific iPSCs derivation in the context of work done in our laboratory and others.