Open AccessBiophysical EPR Studies Applied to Membrane Proteins
Author(s) -
Indra D. Sahu,
Gary A. Lorigan
Publication year - 2015
Publication title -
journal of physical chemistry and biophysics
Language(s) - Uncategorized
Resource type - Journals
ISSN - 2161-0398
DOI - 10.4172/2161-0398.1000188
Subject(s) - electron paramagnetic resonance , membrane protein , bioenergetics , computational biology , chemistry , biological membrane , membrane , nanotechnology , biophysics , biochemical engineering , biology , biochemistry , materials science , engineering , physics , nuclear magnetic resonance , mitochondrion
Membrane proteins are very important in controlling bioenergetics, functional activity, and initializing signal pathways in a wide variety of complicated biological systems. They also represent approximately 50% of the potential drug targets. EPR spectroscopy is a very popular and powerful biophysical tool that is used to study the structural and dynamic properties of membrane proteins. In this article, a basic overview of the most commonly used EPR techniques and examples of recent applications to answer pertinent structural and dynamic related questions on membrane protein systems will be presented.