Open AccessPolyester Fleeces used as an Artificial Interstitium Influence the Spatial Growth of Regenerating Tubules
Author(s) -
Anne Glashauser,
Lucia Denk,
Will W. Minuth
Publication year - 2011
Publication title -
journal of tissue science and engineering
Language(s) - English
Resource type - Journals
ISSN - 2157-7552
DOI - 10.4172/2157-7552.1000105
Subject(s) - regeneration (biology) , polyester , computer science , biology , anatomy , chemistry , microbiology and biotechnology , organic chemistry
In regenerative medicine the use of stem/progenitor cells is a valuable therapeutical option for the regeneration of diseased tissues and organs. However, the secure application of cell-based therapies for the treatment of renal failure requires exact information regarding the mechanisms of parenchyma development in combination with different kinds of biomaterials. Recently, we demonstrated that application of stem/progenitor cells in combination with a polyester fleece I-7 as an artificial interstitium supported the spatial generation of tubules during perfusion culture in chemically defined ®
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