Open AccessAcute Iatrogenic Rhabdomyolisis and Guillan-Barre’ Syndrome: A Dangerous Association
Author(s) -
Elisa Giorli Lucia Briscese
Publication year - 2013
Publication title -
journal of neurology and neurophysiology
Language(s) - English
Resource type - Journals
ISSN - 2155-9562
DOI - 10.4172/2155-9562.1000141
Subject(s) - medicine , omics , association (psychology) , bioinformatics , intensive care medicine , biology , psychology , psychotherapist
Guillan-Barré Syndrome (GBS) is an acute, symmetrical polyneuropathy with a clinical manifestation of flaccid\udparalysis with areflexia and variable sensory disturbance. GBS has an incidence of 1-2 cases/100.000 inhabitants\udfor year. The pathological spectrum of GBS includes Acute Inflammatory Demyelinating Polyneuropathy (AIDP),\udAcute Motor Axonal Neuropathy (AMAN) and Acute Motor Sensory Axonal Neuropathy (AMSAN). We report a case\udof an 81-year-old man with GBS (subtype AMSAN), secondary to a previous Micoplasma Pneumoniae infection, who\udpresented with an elevation of Creatin Kinase (CK) serum levels, and worsened by a co-administration of statins\udand clarithromycin. By our knowledge there are few cases in the literature in which the association of these drugs\udcontributed to worsening GBS