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Classical solutions to a moving boundary problem for an elliptic-parabolic system
Author(s) -
Joachim Escher
Publication year - 2004
Publication title -
interfaces and free boundaries mathematical analysis computation and applications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 39
eISSN - 1463-9971
pISSN - 1463-9963
DOI - 10.4171/ifb/96
Subject(s) - boundary value problem , homogeneous , mathematical analysis , parabolic partial differential equation , mathematics , boundary (topology) , class (philosophy) , free boundary problem , boundary problem , computer science , partial differential equation , combinatorics , artificial intelligence
In this paper we investigate a simple model describing in vivo cancer growth for a single tumor. The model comprises a reaction-diffusion equation describing the evolution of the nutrient concentration, denoted by u, and an elliptic equation for the internal pressure, denoted by p, in the tissue. The cell proliferation rate is denoted by f(u), wheref : R ! R is assumed to be smooth. Typically, this proliferation rate f is assumed to be linear or of logistic type (cf. [6, p. 157] and [7, pp. 190, 193]). A polynomial proliferation rate is proposed in the Appendix of [16]. At time t the tumor occupies the domain(t) with the moving boundary(t) . In dimensionless formp and u satisfy the equations

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