Global existence of solutions for a free boundary problem modeling the growth of necrotic tumors
Author(s) -
Shangbin Cui
Publication year - 2005
Publication title -
interfaces and free boundaries mathematical analysis computation and applications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 39
eISSN - 1463-9971
pISSN - 1463-9963
DOI - 10.4171/ifb/118
Subject(s) - mathematics , mathematical analysis , boundary value problem , nonlinear system , domain (mathematical analysis) , free boundary problem , fixed point theorem , function (biology) , parabolic partial differential equation , schauder fixed point theorem , boundary (topology) , partial differential equation , picard–lindelöf theorem , physics , quantum mechanics , evolutionary biology , biology
In this paper we study a free boundary problem for a reaction-diffusion equation modeling the growth of necrotic tumors. We first reduce this problem into an equivalent initial boundary value problem for a nonlinear parabolic equation on a fixed domain. This parabolic equation is strongly singular in the sense that not only it contains a discontinuous nonlinear function of the unknown function, but also all its coefficients are discontinuous nonlinear functionals of the unknown function. We use the approximation method and the Schauder fixed point theorem combined with L p estimates to prove the existence of a global solution.
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