Molecular Characterization of Norovirus and Rotavirus in Outbreak of Acute Gastroenteritis in Seoul
Author(s) -
Seah Oh,
Sang-Hun Park,
Heejin Ham,
Hyun-Jung Seung,
Jung-Im Jang,
Sangwon Suh,
Sukju Jo,
Sung-Min Choi,
Hae-Sook Jeong
Publication year - 2013
Publication title -
journal of bacteriology and virology
Language(s) - English
Resource type - Journals
eISSN - 2093-0429
pISSN - 1598-2467
DOI - 10.4167/jbv.2013.43.4.307
Subject(s) - norovirus , rotavirus , genotype , diarrhea , acute gastroenteritis , virology , outbreak , epidemiology , molecular epidemiology , medicine , microbiology and biotechnology , biology , virus , gastroenterology , gene , biochemistry
Norovirus and rotavirus are important causes of acute nonbacterial gastroenteritis in communities worldwide. Genotypes of norovirus and rotavirus in stool samples, which were collected from patients, was determined by RT-PCR and ELISA. A total 4,484 stool samples (461 outbreak cases) collected during January 2010-April 2013 were analyzed. Four hundred thirty eight of samples were positive for norovirus. Twelve samples were positive for Rotavirus. Norovirus genotypes identified were nine kinds of G I genotype (G I -1, G I -2, G I -3, G I -4, G I -6, G I -7, G I -9, G I -12, G I -13) and nine kinds of G II genotype(G II -2, G II -4, G II -5, G II -6, G II -7, G II -11, G II -12, G II -15, G II -16). Rotavirus genotypes were G2P[4]. The results might be useful information for evaluating the epidemiological status of viral diarrhea in Seoul, and providing a strategy to prevent human norovirus, rotavirus and other threats to public health in Korea.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom