Open AccessBacterial 23SRibosomal RNA, a Ligand for Toll-like Receptor 13
Author(s) -
Zahid Manzoor,
YoungSang Koh
Publication year - 2012
Publication title -
journal of bacteriology and virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.179
H-Index - 12
eISSN - 2093-0429
pISSN - 1598-2467
DOI - 10.4167/jbv.2012.42.4.357
Subject(s) - 23s ribosomal rna , ribosomal rna , toll like receptor , biology , receptor , rna , pathogen , computational biology , microbiology and biotechnology , innate immune system , genetics , gene , ribosome
Toll-like receptors are required for detection of pathogen-associated molecular patterns and play critical roles in protection of host from infection. Murine TLR13 was recently reported to be involved in recognition of bacterial 23S ribosomal RNA sequence that is the binding site of different antibiotics.
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