Neutrophils in Immunity
Author(s) -
SoYoun Woo
Publication year - 2012
Publication title -
journal of bacteriology and virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.179
H-Index - 12
eISSN - 2093-0429
pISSN - 1598-2467
DOI - 10.4167/jbv.2012.42.2.172
Subject(s) - neutrophil extracellular traps , effector , immunology , autoimmunity , pathogenesis , immunity , extracellular , biology , peripheral blood , inflammation , immune system , medicine , microbiology and biotechnology
Neutrophils are the most abundant white blood cells in the peripheral blood and have long been recognized as the major phagocytes in acute infection by destroying extracellular pathogens. Although research on neutrophils hampered by intractability in the experiments, the newly discovered effector functions of neutrophils includes granular proteins, and cytokines, extracellular traps. With all effector mechanism neutrophils play a critical role in the pathogenesis of acute and chronic infection, autoimmunity and cancer.
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