A Case of Disseminated Intra-abdominal Gastrointestinal Stromal Tumor Managed with Low Dose Imatinib
Author(s) -
Bo Hyun Jang,
ByungWook Kim,
Keun Joon Lim,
Boo Gyoung Kim,
Sung-Min Park,
Joon Sung Kim,
JeongSeon Ji,
Hwang Choi
Publication year - 2015
Publication title -
korean journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.203
H-Index - 25
eISSN - 2233-6869
pISSN - 1598-9992
DOI - 10.4166/kjg.2015.65.6.366
Subject(s) - gist , medicine , imatinib mesylate , stromal tumor , imatinib , adverse effect , gastrointestinal tract , adjuvant therapy , oncology , gastroenterology , surgery , stromal cell , chemotherapy , myeloid leukemia
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. Imatinib mesylate is recommended as adjuvant therapy for GIST after surgical resection. However, drug-related adverse events are common. A 74-year-old female with metastatic GIST who was managed with imatinib experienced severe adverse events, including skin rashes, tremor, and alopecia, etc. The imatinib dose was reduced and the size of the metastatic GIST continued to decrease and adverse events showed significant improvement.
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