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The Effect of Metformin on Responses to Chemotherapy and Survival in Stage IV Colorectal Cancer with Diabetes
Author(s) -
Dong-Jun Lee,
Bun Kim,
Jin Ha Lee,
Su Jung Park,
Sung Pil Hong,
Jae Hee Cheon,
Tae Il Kim,
Won Ho Kim
Publication year - 2012
Publication title -
korean journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.203
H-Index - 25
eISSN - 2233-6869
pISSN - 1598-9992
DOI - 10.4166/kjg.2012.60.6.355
Subject(s) - medicine , metformin , colorectal cancer , hazard ratio , univariate analysis , diabetes mellitus , chemotherapy , cancer , oncology , stage (stratigraphy) , retrospective cohort study , multivariate analysis , gastroenterology , surgery , confidence interval , endocrinology , insulin , paleontology , biology
Metformin is known to lower the risk of cancer and cancer mortality. However, the effect of metformin in stage IV colorectal cancer (CRC) patients with diabetes mellitus (DM) remains unknown. The aim of this study was to evaluate the effect of metformin on tumor response and survival in stage IV CRC patients with DM.

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