A Case of Acute Lymphoblastic Leukemia Presenting with Protein-Losing Enteropathy | Zendy

Seon Young Kim | Zendy; Joong Goo Kwon | Zendy; Myung Hwan Kim | Zendy; Jae Young Oh | Zendy; Jinhong Park | Zendy; Kyung Chan Park | Zendy; Jung Il Ryoo | Zendy; Hun Mo Ryoo | Zendy

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A Case of Acute Lymphoblastic Leukemia Presenting with Protein-Losing Enteropathy

Author(s) -

Seon Young Kim,

Joong Goo Kwon,

Myung Hwan Kim,

Jae Young Oh,

Jinhong Park,

Kyung Chan Park,

Jung Il Ryoo,

Hun Mo Ryoo

Publication year - 2012

Publication title -

korean journal of gastroenterology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.203

H-Index - 25

eISSN - 2233-6869

pISSN - 1598-9992

DOI - 10.4166/kjg.2012.60.5.320

Subject(s) - medicine , hypoproteinemia , protein losing enteropathy , enteropathy , epigastric pain , lymphoblastic leukemia , edema , gastroenterology , acute leukemia , hypoalbuminemia , bone marrow , leukemia , pathology , vomiting , disease

Protein-losing enteropathy (PLE) is a syndrome characterized by excessive gastrointestinal protein loss, resulting in hypoproteinemia and edema. A variety of benign and malignant conditions can be associated with PLE and acute leukemia is a very rare cause of PLE. We report a case of PLE associated with acute lymphoblastic leukemia. A 27-year-old man was admitted due to watery diarrhea, epigastric pain and bilateral leg edema. Laboratory findings showed hypoproteinemia and polycythemia. The diagnosis of PLE and acute lymphoblastic leukemia were confirmed on the measurement of fecal a1-antitrypsin clearance and bone marrow examination. After systemic chemotherapy and autologous stem cell transplantation, his clinical symptoms and abnormal laboratory findings were gradually improved.

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