Anti-inflammatory Mechanism ofLactobacillus rhamnosus GGin Lipopolysaccharide-stimulated HT-29 Cell
Author(s) -
Sang Kil Lee,
Kyung Min Yang,
Jae Hee Cheon,
Tae Il Kim,
Won Ho Kim
Publication year - 2012
Publication title -
korean journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.203
H-Index - 25
eISSN - 2233-6869
pISSN - 1598-9992
DOI - 10.4166/kjg.2012.60.2.86
Subject(s) - lactobacillus rhamnosus , tlr4 , lipopolysaccharide , western blot , tumor necrosis factor alpha , microbiology and biotechnology , inflammation , chemokine , viability assay , iκbα , chemistry , nf κb , biology , cell , probiotic , immunology , gene , bacteria , biochemistry , genetics
Probiotics are live non-pathogenic organisms that belong to the resident microflora, and confer health benefits by multiple mechanisms. Lactobacillus rhamnosus GG (LGG) is one of the probiotic bacteria that ameliorates intestinal injury and inflammation caused by various stimuli. We aimed to evaluate the anti-inflammatory effect and mechanism of LGG in lipopolysaccharide (LPS)-stimulated HT-29 cells.
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