Controlled actuation of therapeutic nanoparticles: an update on recent progress | Zendy

Okhil K. Nag | Zendy; Lauren D. Field | Zendy; YungChia Chen | Zendy; Ajmeeta Sangtani | Zendy; Joyce C. Breger | Zendy; James B. Delehanty | Zendy

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Controlled actuation of therapeutic nanoparticles: an update on recent progress

Author(s) -

Okhil K. Nag,

Lauren D. Field,

YungChia Chen,

Ajmeeta Sangtani,

Joyce C. Breger,

James B. Delehanty

Publication year - 2016

Publication title -

therapeutic delivery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.619

H-Index - 46

eISSN - 2041-6008

pISSN - 2041-5990

DOI - 10.4155/tde-2016-0003

Subject(s) - context (archaeology) , nanotechnology , drug delivery , drug , perspective (graphical) , controlled release , computer science , risk analysis (engineering) , materials science , medicine , pharmacology , artificial intelligence , history , archaeology

A primary envisioned use for nanoparticles (NPs) in a cellular context is for controlled drug delivery where the full benefit of NP attributes (small size, large drug cargo loading capacity) can improve the pharmacokinetics of the drug cargo. This requires the ability to controllably manipulate the release of the drug cargo from the NP vehicle or ‘controlled actuation’. In this review, we highlight new developments in this field from 2013 to 2015. The number and breadth of reports are a testament to the significant advancements made in this field over this time period. We conclude with a perspective of how we envision this field to continue to develop in the years to come.

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