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An Unusual Case of Crescentic Lupus Nephritis Presenting With Normal Renal Function
Author(s) -
Sandhya Manohar,
Chamundeswari Subramanian,
Kameswari Lakshmi
Publication year - 2015
Publication title -
future science oa
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 23
ISSN - 2056-5623
DOI - 10.4155/fso.15.4
Subject(s) - lupus nephritis , medicine , renal function , creatinine , proteinuria , renal biopsy , systemic lupus erythematosus , nephrotic syndrome , kidney , pathology , nephritis , gastroenterology , disease
Lupus nephritis is a life-threatening manifestation of systemic lupus erythematosus (SLE). This is commonly suspected when lupus patients present with elevated serum creatinine levels. But it is important to be aware that even patients with advanced disease in the kidney from SLE can have normal renal function, thus requiring a high index of suspicion. We present the case of a patient who presented with nonspecific musculoskeletal symptoms and was diagnosed with SLE. He also had nephrotic range proteinuria but his serum creatinine was normal. A renal biopsy revealed diffuse proliferative crescentic lupus nephritis. We have reviewed the literature for correlation between crescents; a sign of severe glomerular damage and creatinine levels.

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