Detecting and Monitoring NO, SNO and Nitrite in vivo | Zendy

Landon Bellavia | Zendy; Daniel B. Kim–Shapiro | Zendy; S. Bruce King | Zendy

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Detecting and Monitoring NO, SNO and Nitrite in vivo

Author(s) -

Landon Bellavia,

Daniel B. Kim–Shapiro,

S. Bruce King

Publication year - 2015

Publication title -

future science oa

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 23

ISSN - 2056-5623

DOI - 10.4155/fso.15.36

Subject(s) - in vivo , nitric oxide , nitrite , reactive nitrogen species , nox , chemistry , computational biology , biology , microbiology and biotechnology , nitrate , organic chemistry , combustion

The detection and quantification of nitric oxide and related reactive nitrogen species in vivo is vital to the understanding of the pathology and/or treatment of numerous conditions. To that end, several detection and quantification methods have been developed to study NO, as well as its redox relatives, nitrite and S- nitrosothiols. While no single technique can offer a complete picture of the nitrogen cycle in a given system in vivo , familiarity with the benefits and limitations of several common tools for NO x determination can assist in the development of new diagnostics and therapeutics.

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