Acquired Hemophagocytic Syndrome in a Patient With Synovial Sarcoma: a Case Report | Zendy

Chiara Ciccarese | Zendy; Roberto Ferrara | Zendy; Emanuela Fantinel | Zendy; Camilla Zecchetto | Zendy; Francesca Simionato | Zendy; Elisabetta Grego | Zendy; Silvia Ortolani | Zendy; Mario Caccese | Zendy; Davide Bimbatti | Zendy; Sara Cingarlini | Zendy; Matteo Brunelli | Zendy; A Andreini | Zendy; Giampaolo Tortora | Zendy; Francesco Massari | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Acquired Hemophagocytic Syndrome in a Patient With Synovial Sarcoma: a Case Report

Author(s) -

Chiara Ciccarese,

Roberto Ferrara,

Emanuela Fantinel,

Camilla Zecchetto,

Francesca Simionato,

Elisabetta Grego,

Silvia Ortolani,

Mario Caccese,

Davide Bimbatti,

Sara Cingarlini,

Matteo Brunelli,

A Andreini,

Giampaolo Tortora,

Francesco Massari

Publication year - 2015

Publication title -

future science oa

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 23

ISSN - 2056-5623

DOI - 10.4155/fso.15.27

Subject(s) - hemophagocytosis , hepatosplenomegaly , hemophagocytic lymphohistiocytosis , medicine , hypertriglyceridemia , pathology , complication , immunology , bone marrow , pancytopenia , disease , triglyceride , cholesterol

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome characterized by severe hyperinflammation due to an overwhelming ineffective immune response to different triggers. Most important symptoms are fever, hepatosplenomegaly and cytopenias. Biochemical signs include elevated ferritin, hypertriglyceridemia and low fibrinogen. Hemophagocytosis in the bone marrow is a hallmark of this syndrome. Based on the pathogenetic mechanism, it can be classified into primary (inherited) or secondary (acquired) HLH. We report, to our knowledge, the first case of acquired hemophagocytic syndrome that arose in a 20-year-old man affected by synovial sarcoma as a complication during chemotherapy.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research