Open AccessOpen Access Chemical Probes for Epigenetic Targets
Author(s) -
Peter J. Brown,
Susanne Müller
Publication year - 2015
Publication title -
future medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.708
H-Index - 69
eISSN - 1756-8927
pISSN - 1756-8919
DOI - 10.4155/fmc.15.127
Subject(s) - drug discovery , pharmaceutical industry , epigenetics , computational biology , drug development , data science , computer science , nanotechnology , drug , biology , bioinformatics , pharmacology , genetics , materials science , gene
High attrition rates in drug discovery call for new approaches to improve target validation. Academia is filling gaps, but often lacks the experience and resources of the pharmaceutical industry resulting in poorly characterized tool compounds.
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