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Simplified teixobactin analogues to target superbugs
Author(s) -
Ishwar Singh
Publication year - 2017
Publication title -
future medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.708
H-Index - 69
eISSN - 1756-8927
pISSN - 1756-8919
DOI - 10.4155/fmc-2017-0256
Subject(s) - acinetobacter baumannii , staphylococcus aureus , pseudomonas aeruginosa , microbiology and biotechnology , lipid ii , antimicrobial , klebsiella pneumoniae , chemistry , medicine , bacteria , biology , biochemistry , escherichia coli , bacterial cell structure , genetics , gene
Ishwar Singh speaks to Benjamin Walden, Commissioning Editor. Ishwar Singh is Senior Lecturer in biological chemistry at the School of Pharmacy, University of Lincoln. Prior to Lincoln, he had held many prestigious fellowships such as the Alexander von Humboldt fellowship, Germany; and Senior Research Fellowship, DANIDA, Denmark and CSIR, India. He is an organic chemist. He has developed bioconjugations for DNA, RNA and polymer modifications. He is currently leading research in novel antimicrobials based on rational design against clinically important resistant bacteria (such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, mycobacteria, Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa), biologics delivery, peptides, sequence-selective DNA cross linking, nanoparticles modifications for drug delivery and diagnostic applications.

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