Open AccessAn evolutionary view of chromatography data systems used in bioanalysis
Author(s) -
McDowall Rd
Publication year - 2010
Publication title -
bioanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.566
H-Index - 58
eISSN - 1757-6199
pISSN - 1757-6180
DOI - 10.4155/bio.09.182
Subject(s) - interfacing , bioanalysis , automation , analyte , computer science , chart , simple (philosophy) , instrumentation (computer programming) , process engineering , chromatography , chemistry , engineering , computer hardware , mathematics , philosophy , epistemology , operating system , mechanical engineering , statistics
This is a personal view of how chromatographic peak measurement and analyte quantification for bioanalysis have evolved from the manual methods of 1970 to the electronic working possible in 2010. In four decades there have been major changes from a simple chart recorder output (that was interpreted and quantified manually) through simple automation of peak measurement, calculation of standard curves and quality control values and instrument control to the networked chromatography data systems of today that are capable of interfacing with Laboratory Information Management Systems and other IT applications. The incorporation of electronic signatures to meet regulatory requirements offers a great opportunity for business improvement and electronic working.