Mesenchymal stem cells treatment in COVID-19 patient with multi-organ involvement | Zendy

Rabia Yılmaz | Zendy; Gökhan Adaş | Zendy; Zafer Çukurova | Zendy; Kadriye Kart Yaşar | Zendy; Nilgün Işıksaçan | Zendy; Olga Nehir Öztel | Zendy; Erdal Karaöz | Zendy

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Mesenchymal stem cells treatment in COVID-19 patient with multi-organ involvement

Author(s) -

Rabia Yılmaz,

Gökhan Adaş,

Zafer Çukurova,

Kadriye Kart Yaşar,

Nilgün Işıksaçan,

Olga Nehir Öztel,

Erdal Karaöz

Publication year - 2020

Publication title -

bratislavské lekárske listy/bratislava medical journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.387

H-Index - 32

eISSN - 1336-0345

pISSN - 0006-9248

DOI - 10.4149/bll_2020_139

Subject(s) - mesenchymal stem cell , medicine , central nervous system , transplantation , covid-19 , organ transplantation , pathology , intensive care medicine , bioinformatics , immunology , biology , disease , infectious disease (medical specialty)

The aim of this study is to evaluate the therapeutic effect of mesenchymal stem cells (MSCs) in a severe case of brain and multiple organ involvement in a patient with COVID-19. Here, a 51-year-old male patient with multi-organ involvement due to COVID-19 infection and developing cardiac arrest is presented. MSCs were transplanted to the patient four times systematically and once intrathecally. As a result, the application of MSCs has been found to have a healing effect on organs in this patient with severe COVID-19 infection. In addition, transplantation of MSCs both systematically and intrathecally is considered to be effective in the treatment of the central nervous system (Tab. 2, Fig. 2, Ref. 24). Keywords: mesenchymal stem cell, COVID-19, organ involvement.

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