Predictors of Relapse in a Bupropion Trial for Smoking Cessation in Recently-Abstinent Alcoholics: Preliminary Results Using an Aggregate Genetic Risk Score
Author(s) -
John E. McGeary,
Valerie S. Knopik,
John E. Hayes,
Rohan H. C. Palmer,
Peter M. Monti,
David Kalman
Publication year - 2012
Publication title -
substance abuse research and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.027
H-Index - 22
ISSN - 1178-2218
DOI - 10.4137/sart.s8866
Subject(s) - bupropion , smoking cessation , medicine , abstinence , population , nicotine gum , nicotine , placebo , clinical psychology , psychiatry , environmental health , pathology , alternative medicine
Rates of smoking in the US population have decreased overall, but rates in some groups, including alcoholic smokers, remain high. Many newly sober alcoholics are concerned about their smoking and some attempt to quit. However, quit rates in this population are low. Prior studies suggest risk for relapse in this population may be genetically influenced and that genetic factors may moderate response to treatment.
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