Trace Amine Associated Receptor 1 Modulates Behavioral Effects of Ethanol | Zendy

Laurie J. Lynch | Zendy; Katherine Sullivan | Zendy; Eric J. Vallender | Zendy; James K. Rowlett | Zendy; Donna M. Platt | Zendy; Gregory M. Miller | Zendy

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Trace Amine Associated Receptor 1 Modulates Behavioral Effects of Ethanol

Author(s) -

Laurie J. Lynch,

Katherine Sullivan,

Eric J. Vallender,

James K. Rowlett,

Donna M. Platt,

Gregory M. Miller

Publication year - 2013

Publication title -

substance abuse research and treatment

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.027

H-Index - 22

ISSN - 1178-2218

DOI - 10.4137/sart.s12110

Subject(s) - ethanol , righting reflex , pharmacology , chemistry , knockout mouse , alcohol , medicine , endocrinology , receptor , psychology , reflex , biochemistry

Few treatment options for alcohol use disorders (AUDs) exist and more are critically needed. Here, we assessed whether trace amine associated receptor 1 (TAAR1), a modulator of brain monoamine systems, is involved in the behavioral and reinforcement-related effects of ethanol and whether it could potentially serve as a therapeutic target.

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