Beta-Adrenergic Blockade Therapy for Autonomic Dysfunction is Less Effective for Elderly Patients with Heart Failure and Reduced Left Ventricular Ejection Fraction | Zendy

Ken Shimamoto | Zendy; Masatoshi Kawana | Zendy

Open Access

Beta-Adrenergic Blockade Therapy for Autonomic Dysfunction is Less Effective for Elderly Patients with Heart Failure and Reduced Left Ventricular Ejection Fraction

Author(s) -

Ken Shimamoto,

Masatoshi Kawana

Publication year - 2015

Publication title -

japanese clinical medicine

Language(s) - English

Resource type - Journals

ISSN - 1179-6707

DOI - 10.4137/jcm.s30488

Subject(s) - carvedilol , ejection fraction , medicine , cardiology , heart failure , heart rate variability , sinus rhythm , blockade , heart rate , receptor , blood pressure , atrial fibrillation

Heart rate variability (HRV) has been reported to be an independent predictor of all-cause and sudden cardiac death in patients with heart failure. In the aging heart, however, both autonomic and cardiac functions appear to be altered. We assessed the relationship between aging and responsiveness of HRV and ventricular remodeling to beta-adrenergic blockade therapy in patients with heart failure and reduced ejection fraction (HFREF).

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research