Prostate Cancer Epigenetics: A Review on Gene Regulation | Zendy

Léna Diaw | Zendy; Karen Woodson | Zendy; John W. Gillespie | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Prostate Cancer Epigenetics: A Review on Gene Regulation

Author(s) -

Léna Diaw,

Karen Woodson,

John W. Gillespie

Publication year - 2007

Publication title -

gene regulation and systems biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.534

H-Index - 18

ISSN - 1177-6250

DOI - 10.4137/grsb.s398

Subject(s) - epigenetics , dna methylation , histone , prostate cancer , cancer epigenetics , cancer , disease , biology , bioinformatics , regulation of gene expression , medicine , gene , genetics , cancer research , gene expression , histone methyltransferase

Prostate cancer is the most common cancer in men in western countries, and its incidence is increasing steadily worldwide. Molecular changes including both genetic and epigenetic events underlying the development and progression of this disease are still not well understood. Epigenetic events are involved in gene regulation and occur through different mechanisms such as DNA methylation and histone modifications. Both DNA methylation and histone modifications affect gene regulation and play important roles either independently or by interaction in tumor initiation and progression. This review will discuss the genes associated with epigenetic alterations in prostate cancer progression: their regulation and importance as possible markers for the disease.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research