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pATsi: Paralogs and Singleton Genes from Arabidopsis thaliana
Author(s) -
Luca Ambrosino,
Hamed Bostan,
Pasquale Di Salle,
Mara Sangiovanni,
Alessandra Vigilante,
Maria Luisa Chiusano
Publication year - 2016
Publication title -
evolutionary bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.502
H-Index - 32
ISSN - 1176-9343
DOI - 10.4137/ebo.s32536
Subject(s) - arabidopsis , arabidopsis thaliana , genomics , biology , genome , gene , comparative genomics , computational biology , identification (biology) , genetics , copy number variation , gene duplication , evolutionary biology , ecology , mutant
Arabidopsis thaliana is widely accepted as a model species in plant biology. Its genome, due to its small size and diploidy, was the first to be sequenced among plants, making this species also a reference for plant comparative genomics. Nevertheless, the evolutionary mechanisms that shaped the Arabidopsis genome are still controversial. Indeed, duplications, translocations, inversions, and gene loss events that contributed to the current organization are difficult to be traced. A reliable identification of paralogs and single-copy genes is essential to understand these mechanisms. Therefore, we implemented a dedicated pipeline to identify paralog genes and classify single-copy genes into opportune categories. PATsi, a web-accessible database, was organized to allow the straightforward access to the paralogs organized into networks and to the classification of single-copy genes. This permits to efficiently explore the gene collection of Arabidopsis for evolutionary investigations and comparative genomics.

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